Biomarkers in Toxicology Books

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Biomarkers in Toxicology


Biomarkers in Toxicology
  • Author : Ramesh C. Gupta
  • Publisher : Academic Press
  • Release : 2019-02-13
  • ISBN : 9780128146569
  • Language : En, Es, Fr & De
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Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more

Molecular Biological Markers for Toxicology and Risk Assessment


Molecular Biological Markers for Toxicology and Risk Assessment
  • Author : Bruce A. Fowler
  • Publisher : Academic Press
  • Release : 2016-06-10
  • ISBN : 9780128019016
  • Language : En, Es, Fr & De
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Molecular Biological Markers for Toxicology and Risk Assessment provides an introduction to the exciting field of biomarkers and their use in toxicology and risk assessment. In recent years, new classes of molecular biomarkers capable of detecting early manifestations of ongoing chemical-induced cell injury and cell death have been developed as a result of advances in analytical chemistry, molecular biology, and computational modeling. The interplay between these emergent tools of science has resulted in new insights into initial mechanisms of chemical-induced toxicity and carcinogenicity. Molecular Biological Markers for Toxicology and Risk Assessment guides the reader through a broad range of molecular biological markers, including the "omic" biomarkers, and provides an examination of the various elements in the evolution of these modern tools. It then explores possible ways in which these markers may be applied to advance the field of chemical risk assessment. Since molecular biomarkers and related technologies are inherently complex, the book concludes with a section on risk communication in order that readers may appreciate both the strengths and limitations of molecular biological marker approaches to risk assessment practice. Introduces the use of molecular biomarkers to detect toxic effects of chemicals as early as possible Provides an accessible overview of this emerging, interdisciplinary field, to best inform decision making in chemical and pharmaceutical safety Includes a section on risk communication of these complex concepts, essential for effective risk assessment Provides new insights into the initial mechanisms of chemical-induced toxicity and carcinogenicity

Molecular Biological Markers for Toxicology and Risk Assessment


Molecular Biological Markers for Toxicology and Risk Assessment
  • Author : Bruce A. Fowler
  • Publisher : Academic Press
  • Release : 2016-06-23
  • ISBN : 012809589X
  • Language : En, Es, Fr & De
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"Molecular Biological Markers for Toxicology and Risk Assessment" provides an introduction to the exciting field of biomarkers and their use in toxicology and risk assessment. In recent years, new classes of molecular biomarkers capable of detecting early manifestations of ongoing chemical-induced cell injury and cell death have been developed as a result of advances in analytical chemistry, molecular biology, and computational modeling. The interplay between these emergent tools of science has resulted in new insights into initial mechanisms of chemical-induced toxicity and carcinogenicity." Molecular Biological Markers for Toxicology and Risk Assessment" guides the reader through a broad range of molecular biological markers, including the "omic" biomarkers, and provides an examination of the various elements in the evolution of these modern tools. It then explores possible ways in which these markers may be applied to advance the field of chemical risk assessment. Since molecular biomarkers and related technologies are inherently complex, the book concludes with a section on risk communication in order that readers may appreciate both the strengths and limitations of molecular biological marker approaches to risk assessment practice. Introduces the use of molecular biomarkers to detect toxic effects of chemicals as early as possibleProvides an accessible overview of this emerging, interdisciplinary field, to best inform decision making in chemical and pharmaceutical safetyIncludes a section on risk communication of these complex concepts, essential for effective risk assessmentProvides new insights into the initial mechanisms of chemical-induced toxicity and carcinogenicity

Drug Discovery Toxicology


Drug Discovery Toxicology
  • Author : Yvonne Will
  • Publisher : John Wiley & Sons
  • Release : 2016-03-22
  • ISBN : 9781119053392
  • Language : En, Es, Fr & De
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As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools • Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods • Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices

Biomarkers of Environmental Contamination


Biomarkers of Environmental Contamination
  • Author : 0 McCarthy
  • Publisher : CRC Press
  • Release : 2018-01-18
  • ISBN : 9781351078719
  • Language : En, Es, Fr & De
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How can biological markers help assess and predict human health risks? Find out the answers to this question and others in this timely new book examining the use of biological markers in animals and plants for evaluating the ecological and health effects of environmental contamination. The book explains the concept of environmental sentinels, presents example of field studies and discusses the utility of biomarkers within a risk analysis paradigm. Anyone who needs to know how to assess and predict environmental contamination should consider this book essential reading.