Biomaterials and Medical Device – Associated Infections Books

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Country Situation Analysis


Country Situation Analysis
  • Author : David Porter
  • Publisher :
  • Release : 2001
  • ISBN : 9290212829
  • Language : En, Es, Fr & De
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Materials for Medical Application


Materials for Medical Application
  • Author : Robert B. Heimann
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release : 2020-08-24
  • ISBN : 9783110619249
  • Language : En, Es, Fr & De
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This book gives an introduction to the highly interdisciplinary field of biomaterials. It concisely summarizes properties, synthesis and modification of materials such as metals, ceramics, polymers or composites. Characterization, in vitro and in vivo testing as well as a selection of various applications are also part of this inevitable guide.

Preclinical Evaluation of Antimicrobial Nanodrugs


Preclinical Evaluation of Antimicrobial Nanodrugs
  • Author : Juan Bueno
  • Publisher : Springer Nature
  • Release : 2020-05-08
  • ISBN : 9783030438555
  • Language : En, Es, Fr & De
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Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.

Antibiotic Resistant Bacteria A Challenge to Modern Medicine


Antibiotic Resistant Bacteria  A Challenge to Modern Medicine
  • Author : Sadhana Sagar
  • Publisher : Springer Nature
  • Release : 2019-11-14
  • ISBN : 9789811398797
  • Language : En, Es, Fr & De
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This book summarizes the emerging trends in the field of antibiotic resistance of various gram-negative and gram-positive bacterial species. The ability of different species of bacteria to resist the antimicrobial agent has become a global problem. As such, the book provides a comprehensive overview of the advances in our understanding of the origin and mechanism of resistance, discusses the modern concept of the biochemical and genetic basis of antibacterial resistance and highlights the clinical and economic implications of the increased prevalence of antimicrobial resistant pathogens and their ecotoxic effects. It also reviews various strategies to curtail the emergence and examines a number of innovative therapeutic approaches, such as CRISPR, phage therapy, nanoparticles and natural antimicrobials, to combat the spread of resistance.

Antibacterial Drug Discovery to Combat MDR


Antibacterial Drug Discovery to Combat MDR
  • Author : Iqbal Ahmad
  • Publisher : Springer Nature
  • Release : 2019-11-09
  • ISBN : 9789811398711
  • Language : En, Es, Fr & De
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This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.