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Osteonecrosis


Osteonecrosis
  • Author : Kyung-Hoi Koo
  • Publisher : Springer
  • Release : 2014-07-19
  • ISBN : 9783642357671
  • Language : En, Es, Fr & De
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Osteonecrosis is a disease caused by reduced blood flow to bones in the joints, including the hip, knee, shoulder, and ankle. The disease, which is usually progressive and leads to joint failure, occurs in young adults aged from their twenties to their fifties. The pathogenesis of osteonecrosis is still unclear, and treatment remains controversial. This textbook provides up-to-date and comprehensive information on the pathophysiology, etiology, diagnosis, classification, and treatment of osteonecrosis. The role of various imaging modalities is considered, and both non-surgical and surgical treatment approaches are clearly explained. The contributions, all from experts in the field, are based on presentations at leading international meetings during the past 10 years and on peer-reviewed papers. The book will be of interest not only to clinical practitioners but also to those engaged in basic research.

Ounce of Prevention Mainly for Men


Ounce of Prevention  Mainly for Men
  • Author : Dr Anthony Vendryes
  • Publisher : Tony Vendryes Enterprises Limited
  • Release : 2014-06-12
  • ISBN : 9769570508
  • Language : En, Es, Fr & De
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An Ounce of Prevention - Especially for Women, though well-received, has created a clamour for a book that addressed male health concerns specifically. The discipline of writing a weekly column in the premier Jamaican daily newspaper, the Gleaner for over fifteen years has been very useful. It has caused me to focus on presenting a clear and practical message on specific issues of health and wellness in approximately a thousand words. This book, An Ounce of Prevention - Mainly for Men is a compilation of those messages with the male reader particularly in mind. Some important topics in the earlier book that apply to both men and women have been updated and presented along with new subjects in four sections titled: Healthy Ideas, Healing Agents, Danger Areas and Common Complaints. A fifth section - Male Issues - focuses exclusively on matters of relevance to men. Close to 100 subjects are covered in these five sections. Like the previous volumes, each chapter in this book can be read by itself in any order and it delivers a simple massage on that particular subject. Subject headings are in alphabetical order for easy access. References have been simplified and medical jargon kept to a minimum. The appendix and the useful references section provide support information.

Forthcoming Books


Forthcoming Books
  • Author : Rose Arny
  • Publisher :
  • Release : 1996-10
  • ISBN : UOM:39015023732475
  • Language : En, Es, Fr & De
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Pediatrics in Systemic Autoimmune Diseases


Pediatrics in Systemic Autoimmune Diseases
  • Author : Rolando Cimaz
  • Publisher : Elsevier
  • Release : 2016-06-08
  • ISBN : 9780444635976
  • Language : En, Es, Fr & De
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Pediatrics in Systemic Autoimmune Diseases, Second Edition, provides a good starting point for physicians and scientists new to the field and for anyone looking for the most up-to-date summary of a particular disease. While many questions are answered, many more are raised for which we do not yet have the answers. The book provides inspiration to readers conducting their own research and helps to answer their questions. The care of children with systemic autoimmune diseases is moving forward at a rapid pace. The systemic autoimmune diseases of childhood have always represented a special problem for the physicians and scientists who care for the affected children and study their diseases. Some conditions, such as Kawasaki disease, are virtually unique to childhood, while systemic lupus erythematosus, progressive systemic sclerosis, and juvenile onset spondyloarthropathies may be thought of as the early onset of the same disease which is seen in adults. The autoinflammatory disorders appear to be of clear genetic origin, accounting for their frequent discovery in childhood. For many other conditions, such as juvenile dermatomyositis, the relationship between the conditions seen in children and that seen in adults is less certain. This book explores these phenomena, giving users a foundation on which to understand certain diseases. Includes completely updated chapters and five new chapters Explains the differences in systemic autoimmune diseases seen in children vs. those seen in adults Covers the latest advances in pathogenesis and clinical management of common conditions seen in pediatric rheumatology practices, benefiting both pediatric and adult rheumatologists, as well as physicians from other specialties Brings the reader up-to-date and allows easy access to individual topics in one place Provides the latest information available in a format that would give the clinician both a clear understanding of what has been done in the past and a scientific basis for deciding what to do for the next afflicted child in their care

Preclinical Development Handbook


Preclinical Development Handbook
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release : 2008-03-21
  • ISBN : 9780470249024
  • Language : En, Es, Fr & De
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A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques. Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor has carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: * Modeling and informatics in drug design * Bioanalytical chemistry * Absorption of drugs after oral administration * Transporter interactions in the ADME pathway of drugs * Metabolism kinetics * Mechanisms and consequences of drug-drug interactions Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This publication should be readily accessible to all pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.