Epigenetic Mechanisms in the Brain Books

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Epigenetic Mechanisms in the Brain


Epigenetic Mechanisms in the Brain
  • Author : Andrew J. Kennedy
  • Publisher : Academic Press
  • Release : 2020-06
  • ISBN : 0128164972
  • Language : En, Es, Fr & De
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Epigenetic mechanisms are the biological processes that determine how our genome is used and the same principle can be applied to our neuron genes. In recent findings in the field of neuroepigenetics, it has been determined that our genes encode our memories, transmit information about stressful events, and play apart in our addictions. This book helps to unlock these abstract processes, leading to improved individualized treatments.

Epigenetic Mechanisms in Neural Plasticity


Epigenetic Mechanisms in Neural Plasticity
  • Author : Daniel Ortuño-Sahagún
  • Publisher : Frontiers Media SA
  • Release : 2019-09-20
  • ISBN : 9782889630004
  • Language : En, Es, Fr & De
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Neural plasticity is a unique and adaptive feature of nervous system, which allows neurons to reorganize their interactions in response to a stimulation (intrinsic or extrinsic) to maintain their function. For these reasons, epigenetics emerges as a potential field for developing strategies to modulate changes in pathological situation because extrinsic factors and pharmacological tools can modify neural functioning in organisms during their life. Diet, exercise, environmental aspects, stressors or drugs are available to alter those mechanisms. Epigenetic involves certain molecular signaling pathways, as DNA methylation and histone acetylation and deacetylation, and the emerging non-coding small RNA, mainly microRNA, as a commanders of a number of translation processes. As most of molecular nervous cell alterations, epigenetic mechanisms play an important role in neural plasticity. This eBook collects the burgeoning advances in epigenetic mechanisms, focusing on new insights into cellular and molecular neurobiological mechanisms that underlie brain functioning in health and pathological conditions. Contributions go from basic cellular mechanism to therapeutic opportunities to tackle the challenges on nervous central system development and neurodegeneration.

Genetic and Epigenetic Mechanisms in Down Syndrome Brain


Genetic and Epigenetic Mechanisms in Down Syndrome Brain
  • Author : Jie Lu
  • Publisher :
  • Release : 2013
  • ISBN : OCLC:1154267950
  • Language : En, Es, Fr & De
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Genetic and Epigenetic Mechanisms in Down Syndrome Brain.

Handbook of Neurobehavioral Genetics and Phenotyping


Handbook of Neurobehavioral Genetics and Phenotyping
  • Author : Valter Tucci
  • Publisher : John Wiley & Sons
  • Release : 2017-03-06
  • ISBN : 9781118540718
  • Language : En, Es, Fr & De
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The Handbook of Behavioral Genetics and Phenotyping represents an integrative approach to neurobehavioural genetics; worldwide experts in their field will review all chapters. Advanced overviews of neurobehavioural characteristics will add immense value to the investigation of animal mutants and provide unique information about the genetics and behavioural understanding of animal models, under both normal and pathological conditions. Cross-species comparisons of neurobehavioural phenotypes will pave the way for an evolutionary understanding of behaviour. Moreover, while biological sciences are progressing towards a holistic approach to investigate the complexity of organisms (i.e., “systems biology” approach), an integrated analysis of behavioural phenotyping is still lacking. The Handbook of Behavioral Genetics and Phenotyping strengthens the cross-talk within disciplines that investigate the fundamental basis of behaviour and genetics. This will be the first volume in which traditionally distant fields including genomics, behaviour, electrophysiology, neuroeconomics, and computational neuroscience, among others, are evaluated together and simultaneously accounted for during discussions of future perspectives.

DNA Modifications in the Brain


DNA Modifications in the Brain
  • Author : Timothy W Bredy
  • Publisher : Academic Press
  • Release : 2016-12-23
  • ISBN : 9780128017814
  • Language : En, Es, Fr & De
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DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease. Provides a comprehensive overview of the many facets of DNA modifications Discusses the impact of this dynamic epigenetic mechanism across brain development and lifespan at behavioral, cognitive, molecular and genetic levels Contains contributions by influential leaders in the field Edited by a Neuroscientist to further promote synthesis between epigenetics, neuroscience, and clinical relevance