Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components Books

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Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components


Fighting Multidrug Resistance with Herbal Extracts  Essential Oils and Their Components
  • Author : Mahendra Rai
  • Publisher : Academic Press
  • Release : 2013-05-24
  • ISBN : 9780124017085
  • Language : En, Es, Fr & De
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Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more

Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components


Fighting Multidrug Resistance with Herbal Extracts  Essential Oils and Their Components
  • Author : M.L. Faleiro
  • Publisher : Elsevier Inc. Chapters
  • Release : 2013-05-24
  • ISBN : 9780128066775
  • Language : En, Es, Fr & De
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Aromatic and medicinal plants, through their secondary metabolism, provide a complex mixture of volatile molecules known as essential oils. These volatile molecules exert antibacterial activity that has been used in folk medicine for centuries. During the last few decades, the emergence of antibacterial resistance has forced us to search for new and efficient antimicrobial agents. The significant number of studies on the use of essential oils and their components against multidrug-resistant bacteria, such as Acinetobacter baumannii, methicillin-resistant Staphylococcus aureus, Mycobacterium tuberculosis, and Pseudomonas aeruginosa show the exceptional potential of these natural products to curb the development of antibacterial resistance. Moreover, the use of essential oils and their components in combination with antibiotics may increase bacterial susceptibility, thus limiting resistance.

Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components


Fighting Multidrug Resistance with Herbal Extracts  Essential Oils and Their Components
  • Author : Kateryna Volodymyrivna Kon
  • Publisher : Elsevier Inc. Chapters
  • Release : 2013-05-24
  • ISBN : 9780128066812
  • Language : En, Es, Fr & De
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High prevalence of multidrug-resistant microorganisms in the etiologic structure of different infectious processes significantly decreases the effectiveness of the treatment and enhances the probability of an unfavorable outcome from the infection. Combinations between antibiotics and other antimicrobial agents represent one of the most promising approaches for combating multidrug-resistant bacteria. A high therapeutic potential exists for combinations of antibiotics and natural antimicrobial substances with complex mechanisms of action and multiple healing properties, such as plant essential oils. The purpose of the present chapter is to review published studies on antibiotic-essential oil combinations and discuss the prospects for future studies. In general, many studies have shown the potential for essential oils to act synergistically with antibiotics in vitro. The main proposed mechanism of this beneficial effect is through inhibition of efflux pumps by some essential oils, which restores the activity of the antibiotic. Future efforts should be directed into further studies of antibiotic-essential oil combinations against multidrug-resistant bacteria, with an emphasis on understanding the mechanisms of the produced effect. Combinations of essential oils with different types of antimicrobial agents, such as bacteriophages, nanoparticles, and quorum-sensing inhibitors, require greater attention and are worthy of future investigations.

Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components


Fighting Multidrug Resistance with Herbal Extracts  Essential Oils and Their Components
  • Author : Lyndy McGaw
  • Publisher : Elsevier Inc. Chapters
  • Release : 2013-05-24
  • ISBN : 9780128066843
  • Language : En, Es, Fr & De
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Many bacterial diseases affect animals, causing important economic losses in livestock. Subtherapeutic antibiotic use in production animals as antibiotic growth promoters has been implicated as a causative factor in the development of resistance of bacterial pathogens toward several classes of antimicrobials, some of which are used therapeutically in humans. This has led to the banning of antibiotic growth promoters by the European Union, and such a precedent may be followed in other countries. Alternatives to antibiotic growth promoters are necessary to enable the production of animal protein to keep pace with the expanding world population. One approach is to use plant extracts or essential oils as supplements to provide beneficial effects, including direct antibacterial activity and stimulation of the immune system, or enhancement of ruminal digestion. The risk of resistance developing to a combination of phytochemicals is lower than the risk of resistance against a single antibiotic, and synergistic effects of plant constituents may contribute to the overall activity of the preparation.

Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components


Fighting Multidrug Resistance with Herbal Extracts  Essential Oils and Their Components
  • Author : Román Yesid Ramírez Rueda
  • Publisher : Elsevier Inc. Chapters
  • Release : 2013-05-24
  • ISBN : 9780128066737
  • Language : En, Es, Fr & De
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Methicillin-resistant Staphylococcus aureus (MRSA) is currently one of the most common causes of serious infections, in both hospital and community environments. This type of resistance was discovered in the 1960s, and now (50 years later) it has not been possible to develop an effective therapy to fight against it. This chapter compiles the results of several studies demonstrating the activity (mainly in vitro) of various extracts, essential oils, and plant-derived molecules that can act alone or in combination against MRSA. In addition, natural alternatives (other than from plants) being studied for the same purpose are described. Finally, the important role of phytotherapy in the development of new therapies against multidrug-resistant bacteria such as MRSA is emphasized.