Freeze-Drying of Pharmaceutical and Food Products Books

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Freeze Drying of Pharmaceutical Products


Freeze Drying of Pharmaceutical Products
  • Author : Davide Fissore
  • Publisher : CRC Press
  • Release : 2019-10-24
  • ISBN : 9780429666735
  • Language : En, Es, Fr & De
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Freeze Drying of Pharmaceutical Products provides an overview of the most recent and cutting-edge developments and technologies in the field, focusing on formulation developments and process monitoring and considering new technologies for process development. This book contains case studies from freeze dryer manufacturers and pharmaceutical companies for readers in industry and academia. It was contributed to by lyophilization experts to create a detailed analysis of the subject matter, organically presenting recent advancements in freeze-drying research and technology. It discusses formulation design, process optimization and control, new PAT-monitoring tools, multivariate image analysis, process scale-down and development using small-scale freeze-dryers, use of CFD for equipment design, and development of continuous processes. This book is for industry professionals, including chemical engineers and pharmaceutical scientists.

Freeze Drying of Pharmaceutical and Food Products


Freeze Drying of Pharmaceutical and Food Products
  • Author : Tse-Chao Hua
  • Publisher : Elsevier
  • Release : 2010-07-30
  • ISBN : 9781845697471
  • Language : En, Es, Fr & De
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Freeze-drying is an important preservation technique for heat-sensitive pharmaceuticals and foods. Products are first frozen, then dried in a vacuum at low temperature by sublimation and desorption, rather than by the application of heat. The resulting items can be stored at room temperature for long periods. This informative text addresses both principles and practice in this area. The first chapter introduces freeze-drying. The authors then review the fundamentals of the technique, heat-mass transfer analyses, modelling of the drying process and the equipment employed. Further chapters focus on freeze-drying of food, freeze-drying of pharmaceuticals and the protective agents and additives applied. The final chapter covers the important subjects of disinfection, sterilization and process validation. Freeze-drying of pharmaceutical and food products is an essential reference for food, pharmaceutical and refrigeration engineers and scientists with an interest in preservation techniques. It will also be of use to students in these fields. Addresses the principles and practices used in this important preservation technique Explains the fundamentals of heat-mass transfer analysis, modelling and the equipment used Discusses the importance of disinfection, sterilization and process validation

Freeze drying of Pharmaceuticals and Biopharmaceuticals


Freeze drying of Pharmaceuticals and Biopharmaceuticals
  • Author : Felix Franks
  • Publisher : Royal Society of Chemistry
  • Release : 2008
  • ISBN : 9780854041510
  • Language : En, Es, Fr & De
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Aimed at product and process developers in the biopharmaceutical industry and academia, this is the first book to describe freeze-drying, as related to the pharmaceutical industry.

Freeze Drying


Freeze Drying
  • Author : Georg-Wilhelm Oetjen
  • Publisher : John Wiley & Sons
  • Release : 2008-01-08
  • ISBN : 9783527612499
  • Language : En, Es, Fr & De
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Many modern pharmaceutical and biological products, e.g. blood derivatives, vaccines, cytostatic drugs, antibiotics, bacteria cultures but also consumer goods such as soluble coffee are freeze-dried to transform perishable substances into a form that can be stored and reconstituted to their almost original state without loss of quality. The book describes the up-to-date fundamentals of freeze-drying, not just presenting the process in all its seven steps theoretically, but explaining it with many practical examples. Many years of experience in freeze-drying allow the authors to supply valuable criteria for the selection of laboratory, pilot and production plants, discussing the advantages, drawbacks and limitations of different plant designs. In this second, completely revised edition, process and plant automation are introduced in a separate section and methods to transfer pilot plant qualifications and process data to production are presented. The guidelines for process and plant evaluation and qualifications have been updated and enlarged. Trouble shooting is concentrated in a section of its own and literature has been updated with 100 new quotations to include references as recent as 2002, and 100 new tables and figures have been added.

Freeze Drying Lyophilization Of Pharmaceutical Biological Products Second Edition Revised and Expanded


Freeze Drying Lyophilization Of Pharmaceutical   Biological Products  Second Edition  Revised and Expanded
  • Author : Louis Rey
  • Publisher : CRC Press
  • Release : 2004-01-21
  • ISBN : 9780203021323
  • Language : En, Es, Fr & De
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Thoroughly acquainting the reader with freeze-drying fundamentals, Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products, Second Edition carves practical guidelines from the very latest theoretical research, technologies, and industrial procedures. It delineates the best execution of steps from closure preparation and regulatory control of products to equipment sterilization and process validation. With 13 new chapters providing state-of-the-art information, the book unveils innovations currently advancing the field, including LYOGUARD® packaging for bulk freeze-drying and the irradiation of pharmaceutical and biological products.