Genome Engineering via CRISPR-Cas9 System Books

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Genome Engineering via CRISPR Cas9 System


Genome Engineering via CRISPR Cas9 System
  • Author : Vijai Singh
  • Publisher : Academic Press
  • Release : 2020-02-18
  • ISBN : 9780128181416
  • Language : En, Es, Fr & De
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Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields. Provides basic understanding and a clear picture on how to design, use and implement the CRISPR-Cas9 system in different organisms Explains how to create an animal model for disease research and screening purposes using CRISPR Discusses the application of CRISPR-Cas9 systems in basic sciences, biomedicine, virology, bacteriology, molecular biology, neurology, cancer, industry, and many more

Chromosomal Mutagenesis


Chromosomal Mutagenesis
  • Author : Shondra M. Pruett-Miller
  • Publisher : Humana Press
  • Release : 2016-09-22
  • ISBN : 1493955411
  • Language : En, Es, Fr & De
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This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols. Since the first edition, major advances and discoveries have made chromosomal mutagenesis a widely used technique and one that is available to any molecular biology laboratory, and this collection provides detailed protocols, case-studies, and reviews from thought-leaders in the field. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and fully updated, Chromosomal Mutagenesis, Second Edition aims to help speed scientific discovery and aid in the next advances in the field.

Genome Editing and Engineering


Genome Editing and Engineering
  • Author : Krishnarao Appasani
  • Publisher : Cambridge University Press
  • Release : 2018-07-31
  • ISBN : 9781107170377
  • Language : En, Es, Fr & De
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A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment.

CRISPR Cas Systems


CRISPR Cas Systems
  • Author : Rodolphe Barrangou
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-13
  • ISBN : 9783642346576
  • Language : En, Es, Fr & De
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CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.

Next Generation Plant Breeding


Next Generation Plant Breeding
  • Author : Yelda Ozden Çiftçi
  • Publisher : BoD – Books on Demand
  • Release : 2018-09-26
  • ISBN : 9781789239256
  • Language : En, Es, Fr & De
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Following the green revolution and transgenic crop development, another revolutionary progress has been experienced in plant breeding in the last decade with the application of marker-assisted selection (MAS), next-generation sequencing (NGS), and gene editing techniques together with omic technologies, including genomics, transcriptomics, proteomics, and phenomics. Thus, this book is structured into two sections: "Marker-Assisted Breeding" and "RNA-seq and Gene Editing in Plants," which aim to provide a reference for students, instructors, and scientists on recent innovative advances in plant-breeding programs to cultivate crops for tomorrow.