Macrophages in the Human Body Books

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Macrophages in the Human Body


Macrophages in the Human Body
  • Author : Niels Olson Saraiva Camara
  • Publisher : Academic Press
  • Release : 2021-09-15
  • ISBN : 012821385X
  • Language : En, Es, Fr & De
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Through recent researches, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions Macrophages in the Human Body: A Tissue Level Approach presents a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics. It covers translational aspects where there is research support to indicate the therapeutic potential. Covers translational aspects where there is research support to indicate potential therapeutic potential Aims at presenting a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics Introduces Macrophages generally and dive into the organ/tissue/specific representations covering their phenotype, function, and metabolic characteristics Brings updated aspects of macrophages biology

Janeway s Immunobiology


Janeway s Immunobiology
  • Author : Kenneth Murphy
  • Publisher : Garland Science
  • Release : 2010-06-22
  • ISBN : 0815344570
  • Language : En, Es, Fr & De
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The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Molecular Biology of the Cell


Molecular Biology of the Cell
  • Author : Bruce Alberts
  • Publisher :
  • Release : 2004
  • ISBN : 0815332181
  • Language : En, Es, Fr & De
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Macrophages Biology and Role in the Pathology of Diseases


Macrophages  Biology and Role in the Pathology of Diseases
  • Author : Subhra K. Biswas
  • Publisher : Springer
  • Release : 2014-11-12
  • ISBN : 9781493913114
  • Language : En, Es, Fr & De
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Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morphogenesis and ductal branching in mammary glands. Thus, macrophages are extremely versatile cells that can respond efficiently to tissue micro environmental cues by polarizing to distinct phenotypes, depending on the functions they need to perform. Indeed, functional diversity and plasticity are hallmarks of these cells. Macrophages may also play a detrimental role. An overwhelming body of literature has indicated their crucial role in pathogenesis. The list includes sepsis, cancer, metabolic syndrome, immunodeficiency, auto-immune disease-virtually impacting every major pathology that we know. These observations have suggested macrophages and their related molecules as potential targets in therapeutic applications. Available evidence proclaims macrophages as a key player in homeostasis, host defense and disease. Crucial developments in the past few years call for a re-evaluation and update of our understanding of macrophages. The present book is an endeavour that attempts provide state-of-the art knowledge of these cells in health and disease.

The Resolution of Inflammation


The Resolution of Inflammation
  • Author : Adriano Rossi
  • Publisher : Springer Science & Business Media
  • Release : 2008-03-17
  • ISBN : 376437506X
  • Language : En, Es, Fr & De
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This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.