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Micromixers


Micromixers
  • Author : Nam-Trung Nguyen
  • Publisher : William Andrew
  • Release : 2011-09-17
  • ISBN : 9781437735215
  • Language : En, Es, Fr & De
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The ability to mix minute quantities of fluids is critical in a range of recent and emerging techniques in engineering, chemistry and life sciences, with applications as diverse as inkjet printing, pharmaceutical manufacturing, specialty and hazardous chemical manufacturing, DNA analysis and disease diagnosis. The multidisciplinary nature of this field – intersecting engineering, physics, chemistry, biology, microtechnology and biotechnology – means that the community of engineers and scientists now engaged in developing microfluidic devices has entered the field from a variety of different backgrounds. Micromixers is uniquely comprehensive, in that it deals not only with the problems that are directly related to fluidics as a discipline (aspects such as mass transport, molecular diffusion, electrokinetic phenomena, flow instabilities, etc.) but also with the practical issues of fabricating micomixers and building them into microsystems and lab-on-chip assemblies.With practical applications to the design of systems vital in modern communications, medicine and industry this book has already established itself as a key reference in an emerging and important field. The 2e includes coverage of a broader range of fabrication techniques, additional examples of fully realized devices for each type of micromixer and a substantially extended section on industrial applications, including recent and emerging applications. Introduces the design and applications of micromixers for a broad audience across chemical engineering, electronics and the life sciences, and applications as diverse as lab-on-a-chip, ink jet printing, pharmaceutical manufacturing and DNA analysis Helps engineers and scientists to unlock the potential of micromixers by explaining both the scientific (microfluidics) aspects and the engineering involved in building and using successful microscale systems and devices with micromixers The author's applied approach combines experience-based discussion of the challenges and pitfalls of using micromixers, with proposals for how to overcome them

Analysis and Design Optimization of Micromixers


Analysis and Design Optimization of Micromixers
  • Author : Arshad Afzal
  • Publisher : Springer Nature
  • Release : 2021-01-08
  • ISBN : 9789813342910
  • Language : En, Es, Fr & De
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This book illustrates the computational framework based on knowledge of flow and mass transfer together with optimization techniques to solve problems relevant to micromixing technology. The authors provide a detailed analysis of the different numerical techniques applied to the design of micromixers. Flow and mixing analysis is based on both the Eulerian and Lagrangian approaches; relative advantages and disadvantages of the two methods and suitability to different types of mixing problems are analysed. The book also discusses the various facets of numerical schemes subjected to discretization errors and computational grid requirements. Since a large number of studies are based on commercial computational fluid dynamics (CFD) packages, relevant details of these packages to the mixing problem using them are presented. Numerical optimization techniques coupled with CFD analysis of flow and mixing have proved to be an important tool for micromixers design, and therefore, are an important part of the book. These techniques are presented briefly, and focus is on surrogate modeling and optimization applied to design of micromixers.

Passive Micromixers


Passive Micromixers
  • Author : Kwang-Yong Kim
  • Publisher : MDPI
  • Release : 2018-08-20
  • ISBN : 9783038970071
  • Language : En, Es, Fr & De
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This book is a printed edition of the Special Issue " Passive Micromixers" that was published in Micromachines

Micromixers


Micromixers
  • Author : Nam-Trung Nguyen
  • Publisher : William Andrew
  • Release : 2011
  • ISBN : 9781437735208
  • Language : En, Es, Fr & De
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Introduction -- Fundamentals of Mass Transport in Micro Scale -- Fabrication Technologies -- Micromixers Based on Molecular Diffusion -- Micromixers Based on Chaotic Advection -- Active Micromixers -- Characterization Techniques -- Applications of Micromixers.

Numerical Study of Rapid Micromixers for Lab on a chip Applications


Numerical Study of Rapid Micromixers for Lab on a chip Applications
  • Author : Yiou Wang
  • Publisher :
  • Release : 2007
  • ISBN : OCLC:226241635
  • Language : En, Es, Fr & De
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"Effective mixing of liquids is essential in many applications such as drug delivery, DNA analysis/sequencing, pheromone synthesis in microbioreactors, and biological/chemical agent detections. Rapid mixing can reduce the analysis time and permit high throughput in lab-on-a-chip devices. The main objective of this dissertation in to numerically design a rapid mixer for micro/nanofluidic devices. Three types of micromixers with different driving mechanisms including pressure-driven, electrokinetic-driven and magnetic-particle-driven micromixers as well as a hybrid mixer based on both passive and active mixing mechanisms have been numerically investigated. It is found in the pressure driven micromixer that the relay frequency is a critical factor affecting the micromixing. For the electrokinetic micromixer, the effects of various design parameters such as channel width, relay frequency, external electric potential have been studied. The present study utilized two sets of time-dependent electric fields that are superimposed on a steady (pumping) electric field. The relay technique used in this dissertation not only stretches the fluid streams to increase the interfacial surface area, but also allows a self-sustained flow system for lab-on-a-chip devices. In the hybrid micromixer, the asymmetric serpentine structure plays an active role in ultra-fast mixing within a short distance. With the designed hybrid micromixer, a very high mixing efficiency (95.6%) has been obtained within 1.0 second at x=500 [mu]m for a 50 [mu]m wide channel. Passive serpentine structures, however, induce flow impedance, and it reduces the flow velocity in the micromixer. The difference with the pressure driven and electrokinetic micromixers is that neither one of them can obtain complete mixing in a straight channel; the magnetic-particle-driven micromixer with a simple actuation configuration studied in this dissertation is proved to be an effective mixer. The numerical simulations have shown that a magnetic micromixer consisting of a microchannel and a pair of electromagnets yields a very high mixing efficiency (>95%) within a short period of time (1 second). The effects of various design parameters such as applied magnetic actuation force and operating frequency have been studied in magnetic mixing. The numerical results of the magnetic-particle-actuated mixer demonstrate that a simple micromixer configuration is sufficient for a complete micromixing within a short distance and time period, with no need to fabricate complex serpentine channels. This simple mixing scheme not only provides an excellent mixing, even in a simple microchannel, but is also easily applied to 'lab-on-a-chip' applications with a pair of external electromagnets. In summary, the investigation in this dissertation reflects that both the hybrid electrokinetic mixer and magnetic mixer are very efficient and can be applied to meet the requirements of high throughput biosensor. It is believed that this research will provide guidance for the design of state-of-art of the micromixers for on-chip biosensor systems."--Abstract.