Nucleic Acids Books

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Principles of Nucleic Acid Structure


Principles of Nucleic Acid Structure
  • Author : Stephen Neidle
  • Publisher : Elsevier
  • Release : 2010-07-26
  • ISBN : 0080553524
  • Language : En, Es, Fr & De
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This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software. Completely updated with expanded discussion of topics such as RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA) Includes a complete list of resources, including relevant online databases and software Defines technical lingo for novices

Nucleic Acids in Chemistry and Biology


Nucleic Acids in Chemistry and Biology
  • Author : G. Michael Blackburn
  • Publisher : Royal Society of Chemistry
  • Release : 2006-01-01
  • ISBN : 9780854046546
  • Language : En, Es, Fr & De
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The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved. Revised and updated Nucleic Acids in Chemistry and Biology 3rd Edition discusses in detail, both the chemistry and biology of nucleic acids and brings RNA into parity with DNA. Written by leading experts, with extensive teaching experience, this new edition provides some updated and expanded coverage of nucleic acid chemistry, reactions and interactions with proteins and drugs. A brief history of the discovery of nucleic acids is followed by a molecularly based introduction to the structure and biological roles of DNA and RNA. Key chapters are devoted to the chemical synthesis of nucleosides and nucleotides, oligonucleotides and their analogues and to analytical techniques applied to nucleic acids. The text is supported by an extensive list of references, making it a definitive reference source. This authoritative book presents topics in an integrated manner and readable style. It is ideal for graduate and undergraduates students of chemistry and biochemistry, as well as new researchers to the field.

Nucleic Acids


Nucleic Acids
  • Author : Victor A. Bloomfield
  • Publisher : Sterling Publishing Company
  • Release : 2000-04-17
  • ISBN : 0935702490
  • Language : En, Es, Fr & De
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This is a comprehensive and up-to-date account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function. The book has been carefully organised to meet the needs of molecular biologists, physical biochemists and physical chemists with only a basic understanding of physical chemistry and molecular biology. Nucleic Acids will serve as a textbook in physical biochemistry and biophysical chemistry classes, as well as a supplemental text in courses on nucleic acid biochemistry or molecular biology, and as a personal reference for students and researchers in these fields.

Nucleic Acids in Immunology


Nucleic Acids in Immunology
  • Author : O. J. Plescia
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 9783642876684
  • Language : En, Es, Fr & De
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Two fields have played a leading role in biomedical research in recent years, the biochemistry of nucleic acids and immunology. Yet, with the exception of those aspects which have been concerned with antibody synthesis as an example of protein synthesis, there was until recently a lack of direct association between the two fields. Until quite recently the antigenicity of nucleic acids was still in doubt and indeed represented a controversial subject. Also, the exact role of the various nucleic acids in various stages of antibody synthesis was uncertain. These skepticisms and uncertainties disappeared rapidly in the last few years. New experi mental approaches brought the realization that nucleic acids, under appropriate conditions, are indeed immunogenic, and that the resulting antibodies can furnish new tools for the exploration of the mplecular structure of the all-important family of nucleic acid molecules. ' At the same time, the recognition of the antigenicity of nucleic acids brought a new level of understanding to certain auto-immune diseases and pro vided new material for the exploration of the role of a carrier in immune responses. Side by side with this development was the almost explosive development of new experimental approaches and new ideas pertaining to the problem of antibody formation. Nucleic acids in their various forms were recognized as playing an expected major role in the activation of antibody-forming cells. Perhaps less to be expected was the role they can playas non-specific stimulators of antibody formation.

Electrochemistry of Nucleic Acids and Proteins


Electrochemistry of Nucleic Acids and Proteins
  • Author : Emil Paleček
  • Publisher : Elsevier
  • Release : 2005
  • ISBN : 9780444521507
  • Language : En, Es, Fr & De
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DNA (sometimes referred to as the molecule of life), is the most interesting and most important of all molecules. Electrochemistry of Nucleic Acids and Proteins: Towards Electrochemical Sensors for Genomics and Proteomics is devoted to the electrochemistry of DNA and RNA and to the development of sensors for detecting DNA damage and DNA hybridization. Volume 1, in the brand new series Perspectives in Bioanalysis, looks at the electroanalytical chemistry of nucleic acids and proteins, development of electrochemical sensors and their application in biomedicine and in the new fields of genomics and proteomics. The authors have expertly formatted the information for a wide variety of readers, including new developments that will inspire students and young scientists to create new tools for science and medicine in the 21st century. * Covers highly sophisticated methods of electrochemical analysis of nucleic acids and proteins * Summarises the present state of electrochemical analysis of nucleic acids and proteins * Includes future trends in the electrochemical analysis in genomics and proteomics