Oral Delivery of Insulin Books

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Oral Delivery of Insulin


Oral Delivery of Insulin
  • Author : T.A. Sonia
  • Publisher : Elsevier
  • Release : 2014-12-11
  • ISBN : 9781908818683
  • Language : En, Es, Fr & De
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Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. Presents an overview of Diabetes Mellitus Includes a discussion of various strategies and techniques adopted for oral delivery of insulin Presents an update of research in the field

Oral Delivery of Insulin


Oral Delivery of Insulin
  • Author : T. A. Sonia
  • Publisher : Woodhead Publishing
  • Release : 2017-11-13
  • ISBN : 0081016255
  • Language : En, Es, Fr & De
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Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. Presents an overview of Diabetes MellitusIncludes a discussion of various strategies and techniques adopted for oral delivery of insulinPresents an update of research in the field

Application of Nanotechnology in Drug Delivery


Application of Nanotechnology in Drug Delivery
  • Author : Ali Demir Sezer
  • Publisher : BoD – Books on Demand
  • Release : 2014-07-25
  • ISBN : 9789535116288
  • Language : En, Es, Fr & De
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This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Novel Drug Delivery Systems for the Delivery of Insulin


Novel Drug Delivery Systems for the Delivery of Insulin
  • Author : Radhika Narain
  • Publisher :
  • Release : 2016-09-15
  • ISBN : 366829707X
  • Language : En, Es, Fr & De
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Scientific Study from the year 2014 in the subject Medicine - Pharmacology, grade: A, language: English, abstract: The delivery of proteins is challenging due to their high molecular weight and hydrophilic structures, making them difficult to cross the ubiquitous lipidic membranes. Proteins have a unique structure which makes them suited to a unique function, therefore, maintenance of the structural integrity and stability of these macromolecules is also of a high concern as they can easily be denatured by temperature, pH and other physiochemical changes. The protein and peptide delivery systems have to be designed in a way such that the drug carriers can protect the protein from proteases, increase its permeability through membranes, increase its absorption and bioavailability, sustain its release, with low dosage requirements and, increase its systemic circulation. The study presents the delivery of insulin through various routes: buccal, transdermal, oral and pulmonary, utilizing different novel carriers like polymeric nanoparticles, solid lipid nanoparticles, liposomes, nanoshells, nanospheres and nanoparticles encapsulated in microparticles, along with drug surface modification either by attaching peptide ligands or conjugating with polymers to enhance absorption and targeting capacity of the drug.

Oral Controlled Release Formulation Design and Drug Delivery


Oral Controlled Release Formulation Design and Drug Delivery
  • Author : Hong Wen
  • Publisher : John Wiley & Sons
  • Release : 2011-01-14
  • ISBN : 1118060326
  • Language : En, Es, Fr & De
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This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.