Rosenberg’s Molecular and Genetic Basis of Neurological and Psychiatric Disease Books

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Neurogenesis and Neural Plasticity


Neurogenesis and Neural Plasticity
  • Author : Catherine Belzung
  • Publisher : Springer Science & Business Media
  • Release : 2014-07-08
  • ISBN : 9783642362323
  • Language : En, Es, Fr & De
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This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.

Oxidative Stress


Oxidative Stress
  • Author : Helmut Sies
  • Publisher : Academic Press
  • Release : 2019-11-07
  • ISBN : 9780128196960
  • Language : En, Es, Fr & De
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Oxidative Stress: Eustress and Distress presents current knowledge on oxidative stress within the framework of redox biology and translational medicine. It describes eustress and distress in molecular terms and with novel imaging and chemogenetic approaches in four sections: A conceptual framework for studying oxidative stress. Processes and oxidative stress responses. Signaling in major enzyme systems (oxidative eustress), and damaging modification of biomolecules (oxidative distress). The exposome addresses lifelong exposure and impact on health, nutrient sensing, exercise and environmental pollution. Health and disease processes, including ischemia-reperfusion injury, developmental and psychological disorders, hepatic encephalopathy, skeletal muscle disorders, pulmonary disease, gut disease, organ fibrosis, and cancer. Oxidative Stress: Eustress and Distress is an informative resource useful for active researchers and students in biochemistry, molecular biology, medicinal chemistry, pharmaceutical science, nutrition, exercise physiology, analytical chemistry, cell biology, pharmacology, clinical medicine, and environmental science. Characterizes oxidative stress within the framework of redox biology, redox signaling, and medicine. Empowers researchers and students to quantify specific reactants noninvasively, identify redox biomarkers, and advance translational studies. Features contributions from international leaders in oxidative stress and redox biology research.

Adaptation in Natural and Artificial Systems


Adaptation in Natural and Artificial Systems
  • Author : John Henry Holland
  • Publisher : MIT Press
  • Release : 1992
  • ISBN : 0262581116
  • Language : En, Es, Fr & De
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List of figures. Preface to the 1992 edition. Preface. The general setting. A formal framework. lustrations. Schemata. The optimal allocation of trials. Reproductive plans and genetic operators. The robustness of genetic plans. Adaptation of codings and representations. An overview. Interim and prospectus. Glossary of important symbols.

Autophagy in Health and Disease


Autophagy in Health and Disease
  • Author : Kursad Turksen
  • Publisher : Springer
  • Release : 2018-10-06
  • ISBN : 9783319981468
  • Language : En, Es, Fr & De
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This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases. The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing clinicians and advanced graduate students.

Targets Tracers and Translation Novel Radiopharmaceuticals Boost Nuclear Medicine


Targets  Tracers and Translation     Novel Radiopharmaceuticals Boost Nuclear Medicine
  • Author : Gerald Reischl
  • Publisher : MDPI
  • Release : 2019-09-20
  • ISBN : 9783039213139
  • Language : En, Es, Fr & De
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This is the fourth Special Issue in Pharmaceuticals within the last six years dealing with aspects of radiopharmaceutical sciences. It demonstrates the significant interest and increasing relevance to ameliorate nuclear medicine imaging with PET or SPECT, and also radiotherapeutical procedures.Numerous targets and mechanisms have been identified and have been under investigation over the previous years, covering many fields of medical and clinical research. This development is well illustrated by the articles in the present issue, including 13 original research papers and one review, covering a broad range of actual research topics in the field of radiopharmaceutical sciences.