Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease Books

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Sialic Acids and Sialoglycoconjugates in the Biology of Life Health and Disease


Sialic Acids and Sialoglycoconjugates in the Biology of Life  Health and Disease
  • Author : Shyamasree Ghosh
  • Publisher : Academic Press
  • Release : 2020-02-15
  • ISBN : 0128161264
  • Language : En, Es, Fr & De
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Sialic Acids and Sialoglycoconjugates in the Biology of life, Health and Disease provides insight in the latest knowledge developed in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesised post translationally they play important role in recognition, signalling, immunological response and cell-cell interaction. Sialioglycoconjugates form an important biomarker in disease. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era sialoglybiology has become more and more important in deciphering a health and disease condition. Sialic Acids and Sialoglycoconjugates in the Biology of life, Health and Disease enables the reader to understand the role of sialylation as post translational modification. Discusses the sialic acid and their role in different diseases other than cancer Provides understanding to sialylations as post translational modifications (PTM) Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health Gives insight in the importance of sialic acid biology through animal models

Sialic Acids and Sialoglycoconjugates in the Biology of Life Health and Disease


Sialic Acids and Sialoglycoconjugates in the Biology of Life  Health and Disease
  • Author : Shyamasree Ghosh
  • Publisher : Academic Press
  • Release : 2020-01-08
  • ISBN : 9780128161272
  • Language : En, Es, Fr & De
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Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions. Discusses the sialic acids and their role in different diseases (other than cancer) Provides an understanding of sialylations as post translational modifications (PTM) Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health Gives insights on the importance of sialic acid biology through animal models

Stem Cells


Stem Cells
  • Author : Suchandra Chowdhury
  • Publisher : Springer Nature
  • Release : 2021-08-25
  • ISBN : 9789811616389
  • Language : En, Es, Fr & De
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Stem cells hold great promise for cell therapy, tissue engineering, regenerative medicine and pharmaceutical and biotechnological applications. This book highlights the potency of stem cells, their property of self-renewal and their ability to differentiate into different cell lineages. It further describes the different markers to identify stem cells, sources, methods of isolation, culture including 2D, 3D and beyond and their cryopreservation. This is among the first books to discuss glycosylation and sialylation in stem cells. Chapters describe application of stem cells in regenerative medicine and therapy, and highlight their application in cancer therapy and spinal cord injury. The book talks about the important patents on stem cells. The book also highlights the plant stem cells, discussing their pluoripotent nature, role in organ regeneration after injury, specific stem cell niches, that signals to block differentiation studied in plants shoot, root, and vascular meristems, differentiation of plant stem cell, transcriptional regulation and epigenetic modification of plant stem cells. This book is exciting and cutting edge. It will be of great interest to doctors, students and researchers in the field of regenerative medicine, cancer , biotechnology and plant sciences.

Essentials of Glycobiology


Essentials of Glycobiology
  • Author : Ajit Varki
  • Publisher : CSHL Press
  • Release : 1999
  • ISBN : 0879696818
  • Language : En, Es, Fr & De
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Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Sialic Acids


Sialic Acids
  • Author : Roland Schauer
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 9783709186800
  • Language : En, Es, Fr & De
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Rapid progress in the field of sialic acids has made it desirable to collect the new data about these unique sugars and to continue the series of books on this topic. In 1960, A. GOTTSCHALK wrote "The Chemistry and Biology of Sialic Acids and Related Substances" (Cambridge University Press) and in 1976, A. ROSENBERG and C. -L. SCHENGRUND published "Biological Roles of Sialic Acids" (Plenum Press). In this book emphasis is given to various modern methods used in the isolation and analysis of sialic acids. New approaches to the synthesis of free and bound sialic acids are described and the vast field of occurrence and metabolism of these substances is reviewed. Sialidoses are dealt with in one of the chapters, because sialidases have been recognized as factors of pathophysiological im portance. As knowledge is increasing about the involvement of sialic acids in many aspects of cell biology, another chapter is devoted to these phenomena. With this book I intend to demonstrate modern trends in sialic acid chemistry and biochemistry, and I hope that it will be of practical use and find its place in laboratories rather than in libraries. This publication offers an opportunity to thank all colleagues in many countries, including my coworkers at the universities of Bochum and Kiel, for their cooperation, stimulating discussions and, very important, useful criticism. The continuous cooperation with J. F. G. VLIEGENTHART and his coworkers, Utrecht, has been rewarding in many respects.