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The Chemistry of Heterocycles


The Chemistry of Heterocycles
  • Author : Vishnu Ji Ram
  • Publisher : Elsevier
  • Release : 2019-05-15
  • ISBN : 9780081010334
  • Language : En, Es, Fr & De
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Heterocycles are ubiquitously present in nature and occupy a unique place in organic chemistry as they are part of the DNA and haemoglobin that make life possible. The Chemistry of Heterocycles covers an introduction to the topic, followed by a chapter on the nomenclature of all classes of isolated, fused and polycyclic heterocycles. The third chapter delineates the highly strained three membered N,O and S containing aromatic and non-aromatic heterocycles with one and more than one similar and dissimilar heteroatom. The four-membered heterocycles are abundantly present in various natural and synthetic products of pharmacological importance. This chapter describes the natural abundance, synthesis, chemical reactivity, structural features and their medicinal importance. This class of compounds are present as sub-structures in penicillin and cytotoxic Taxol. Lastly, a chapter on the natural abundance, synthesis, chemical reactivity and pharmacological importance of 5-membered heterocycles with N,O,S heteroatom is covered. The chemistry of heterocycles with mixed heteroatom such as, N-S, N-O, N-S etc. is also described. Gives in-depth, clear information about various systems of nomenclature along with widely acceptable IUPAC system for naming various classes of heterocycles Provides complete information about natural occurrences, synthesis, chemical reactivity, pharmacological importance of heterocycles and their application in material science Highly relevant for graduate students and researchers, providing updated information about various isolated and fused N,O and,S containing heterocycles

The Chemistry of Heterocycles


The Chemistry of Heterocycles
  • Author : Vishnu Ji Ram
  • Publisher : Elsevier
  • Release : 2019-06-06
  • ISBN : 9780128192115
  • Language : En, Es, Fr & De
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The Chemistry of Heterocycles: Chemistry of Six to Eight Membered N,O, S, P and Se Heterocycles details the chemistry, behavior and potential of these important structures. The book presents a practical guide to international nomenclature, including discussions of fused ring systems, heteroatoms with abnormal valences, and bridged, spiro and polycyclic heterocycles. Three membered heterocycles are then the focus, along with their thermodynamic properties and importance in natural products, medicines, materials, and their unique aspects, such as strain, basicity and reactivity. Additional chapters cover 100 key heterocycle structures, from Azetidines, Pyrroles and Pyridines, to Benzoxepines and Oxocanes. Final chapters explore cutting-edge advances in the development of phosphorus and selenium based heterocycles. Provides clear, detailed information on each heterocyclic group, including structural features, such as ring strain, basicity, synthesis and reactivity towards electrophilic and nucleophilic reagents Highlights the latest advances in the field, including phosphorous and selenium-based heterocycles supported by numerous illustrations Includes details of functionalized heterocycles used as synthons for the construction of various arenes and heteroarenes

The Chemistry of Heterocycles


The Chemistry of Heterocycles
  • Author : Theophil Eicher
  • Publisher : John Wiley & Sons
  • Release : 2013-02-26
  • ISBN : 9783527669868
  • Language : En, Es, Fr & De
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This classical textbook in the best sense of the word is now completely revised, updated and with more than 40% new content. The approved ordering system according to the ring size of the heterocycles has been retained, while the important chapter on 'Problems and their Solutions' has been almost completely renewed by introduction of up-to-date scientific exercises, resulting in a great tool for self-testing and exams. There was maintained a chapter on nomenclature and a helpful index of name reactions. With approximately 1,000 new literature citations, this book remains a brilliant gateway to modern heterocyclic science for master and graduate students, as well as PhDs and researchers entering the field. 'If you want quick information about the basic (or acidic!) properties of a heterocycle, some interesting facts, or an assorted few ways of making it, this book provides a welcoming, accurate, and concise introduction.' Angewandte Chemie IE 'Eicher and Hauptmann provide an up to date introduction to the field for the advanced undergraduate and graduate students. ... The book is carefully produced to a very high standard.' European Journal of Medicinal Chemistry

The Chemistry of Heterocycles


The Chemistry of Heterocycles
  • Author : Theophil Eicher
  • Publisher : Wiley-VCH
  • Release : 2002-08-01
  • ISBN : 3527308873
  • Language : En, Es, Fr & De
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The heterocycles are the largest group of organic compounds and this monograph represents a comprehensive survey of this vast field. The discussion is backed by numerous lucid diagrams while the extensive reaction schemes are supported by pertinent references. The text treats aromatic and nonaromatic heterocycles according to ring size under six defined headings for easy location and comparison, and also includes natural occurrence, synthetic aspects and applications in the chemical and pharmaceutical industries. An invaluable reference for advanced undergraduate and graduate students of chemistry and related subjects, this is equally an important aid to professional chemists and teachers of chemistry. Belongs on the shelf of every university library and in laboratories dealing with any aspect of heterocyclic chemistry.

Name Reactions in Heterocyclic Chemistry


Name Reactions in Heterocyclic Chemistry
  • Author : Jie Jack Li
  • Publisher : John Wiley & Sons
  • Release : 2004-12-27
  • ISBN : 9780471704140
  • Language : En, Es, Fr & De
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Covers important name reactions relevant to heterocyclic chemistry The field of heterocyclic chemistry has long presented a specialchallenge for chemists. Because of the enormous amount and varietyof information, it is often a difficult topic to cover forundergraduate and graduate chemistry students, even in simplifiedform. Yet the chemistry of heterocyclic compounds and methods fortheir synthesis form the bedrock of modern medicinal chemical andpharmaceutical research. Thus there is a great need for highquality, up-to-date, and authoritative books on heterocyclicsynthesis helpful to both the professional research chemist as wellas the advanced student. Name Reactions in Heterocyclic Chemistry provides aone-stop repository for this important field of organic chemistry.The primary topics include three- and four-membered heterocycles,five-membered heterocycles including indoles, furans, thiophenes,and oxazoles, six-membered heterocycles including quinolines,isoquinolines, and pyrimidines, and other heterocycles. Each name reaction is summarized in seven sections: Description Historical perspective Mechanism Variations and improvements Synthetic utility Experimental References Authored by a team of world-renowned contributors - some of whomhave discovered the very reactions they describe - NameReactions in Heterocyclic Chemistry represents astate-of-the-art resource for students and researchers alike.