The Microbiome in Prenatal and Neonatal Life Books

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The Microbiome in Prenatal and Neonatal Life


The Microbiome in Prenatal and Neonatal Life
  • Author : Josef Neu
  • Publisher : Academic Press
  • Release : 2020-12-15
  • ISBN : 0128205903
  • Language : En, Es, Fr & De
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The Microbiome in Prenatal and Neonatal Life clarifies that the microbiome in the maternal fetal unit and immediate changes that occur as new microbes are acquired postnatally play major roles in subsequent health and disease. Rapidly developing technologies for multi-omic analyses and systems biology are shifting paradigms in both scientific knowledge and clinical care with regard to this topic. In essence, we are changing the idea that newborns emerge from sterile environments. As such, in-utero colonization may have impacts on the development of immunity and metabolism that, with epigenetic modifications, will lead to diseases in later life. In addition, the microbial profile that develops during and after birth depends on mode of delivery, type of feeding (human milk versus formula), and various other environmental factors to which the newborn is exposed. Discusses the critical nonredundant timeframe in a newborn's life during which many factors drive immune and tissue maturation and influence the susceptibility to immune-mediated and other diseases in adult life Proves that the fetus and uterine membranes are exposed to not only microbes in close proximity but also to microbial products from metabolism of microbes in the mother Shows that since early life periods are a critical window for development, epigenetic and/or immunologic alterations may occur that can affect not only the infant during his/her lifetime but also subsequent generations Gives insight into factors that may affect the newborn microbiome and subsequent development

Fetal and Neonatal Physiology E Book


Fetal and Neonatal Physiology E Book
  • Author : Richard A. Polin
  • Publisher : Elsevier Health Sciences
  • Release : 2016-05-11
  • ISBN : 9780323352321
  • Language : En, Es, Fr & De
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Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice. The 5th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Chapters devoted to clinical correlation help explain the implications of fetal and neonatal physiology. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Features a fantastic new 4-color design with 1,000 illustrations, 170+ chapters, and over 350 contributors. 16 new chapters cover such hot topics as Epigenetics; Placental Function in Intrauterine Growth Restriction; Regulation of Pulmonary Circulation; The Developing Microbiome of the Fetus and Newborn; Hereditary Contribution to Neonatal Hyperbilirubinemia; Mechanistic Aspects of Phototherapy for Neonatal Hyperbilirubinemia; Cerebellar Development; Pathophysiology of Neonatal Sepsis; Pathophysiology of Persistent Pulmonary Hypertension of the Newborn; Pathophysiology of Meconium Aspiration Syndrome; Pathophysiology of Ventilator Dependent Infants; Pathophysiology of Hypoxic-Ischemic Brain Injury; Pathophysiology of Neonatal White Matter Injury; Pathophysiology of Meningitis; Pathophysiology of Preeclampsia; and Pathophysiology of Chorioamnionitis. New Pathophysiology of Neonatal Diseases section highlights every process associated with a disease or injury, all in one place. In-depth information, combined with end-of-chapter summaries, enables deep or quick use of the text.

Leifer s Introduction to Maternity Pediatric Nursing in Canada E Book


Leifer s Introduction to Maternity   Pediatric Nursing in Canada E Book
  • Author : Gloria Leifer
  • Publisher : Elsevier Health Sciences
  • Release : 2019-09-06
  • ISBN : 9781771722070
  • Language : En, Es, Fr & De
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Gain a solid foundation in Canadian maternity and pediatric nursing! Written in a clear, concise, friendly style, Leifer’s Intro to Maternity & Pediatric Nursing in Canada, is the first Canadian edition of the best-selling Leifer textbook. Fully revised by author, Lisa Keenan-Lindsay, RN, MN, PNC(C), it includes Canadian statistics, terminology, references, guidelines, resources, Canadian nursing best practices, assessments, and more! It’s organized by developmental stages and includes discussions of pediatric disorders by body system from simple-to-complex and health-to-illness. With a rich focus on family health, this text contains exam-style review questions, case studies, and numerous other pedagogical features to give you the tools you need to successfully care for patients within the Canadian social and institutional context. Logical organization of content by simple-to-complex and health-to-illness, makes it easy for you to locate and access information. Health Promotion Considerations boxes focus on preventive strategies for achieving prenatal wellness, health during pregnancy, postpartum health, newborn health, and pediatric illness prevention and wellness---including Canadian immunization schedules for all ages. Unfolding Case Studies with open-ended critical thinking questions assess application of content to practice as you follow one family through conception and the birth process. Nursing Care Plans provide expected outcomes, interventions, and rationales for nursing interventions. Comprehensive coverage of over 35 skills, outlined in step-by-step format cover a wide range of maternal and pediatric nursing interventions. Focus on health promotion and illness prevention, covers women’s health issues, and growth and development of child and parent. Cultural considerations applied as they relate to maternal/infant, and pediatric care in detailed tables. Safety Alerts emphasize protecting patients, family, health care providers, and the public from accidents, medication errors, and the spread of disease. Nursing Tips throughout text provide you with pertinent information applicable in the clinical setting.

The Human Microbiome in Early Life


The Human Microbiome in Early Life
  • Author : Omry Koren
  • Publisher : Academic Press
  • Release : 2020-09-25
  • ISBN : 9780128180983
  • Language : En, Es, Fr & De
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The Human Microbiome in Early Life: Implications to Health and Disease presents recent research advances that have highlighted the significance of early life, possibly beginning before birth, in the establishment of both the microbiome and its role in health and disease. The book reviews current knowledge on the origins of the human microbiota in early life, presents exposures which may disturb normal microbial colonization, and covers their implications to the risk of disease. Finally, emerging means to modify the early human microbiome to improve health are discussed. Examines the timeline of the human microbiome, from before conception to infancy, with an emphasis on clinical implications Evaluates the effort to understand not only the composition but also the origin of the microbiome Proves the emerging means to modify the human microbiome and particularly ‘the first 1000 days of life’ improve human health and prevent disease Generates resources to facilitate characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease

Microbiota in health and disease from pregnancy to childhood


Microbiota in health and disease  from pregnancy to childhood
  • Author : Pamela D. Browne
  • Publisher : Wageningen Academic Publishers
  • Release : 2017-07-20
  • ISBN : 9789086868391
  • Language : En, Es, Fr & De
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This book offers a state-of-the-art overview of the vital relationship between human microbiota and infant and child health. Renowned clinical-experimental experts in this field discuss the development of microbiota during early life and review the environmental inputs that affect the developing infant’s gut microbiota, such as early diet and (postnatal) medical interventions. They further describe the interplay between gut microbiota and functional systems of the body, from the immune system to the central nervous system. The book discusses a range of infant and childhood diseases that are associated with microbial changes or dysbiosis, such as gastrointestinal disorders, allergic diseases, autoimmune disorders and respiratory disorders. Additionally mechanisms by which microbial dysbiosis may influence behaviour in infants are discussed. Other topics include the use of current tools in molecular microbiology for microbiota-related research and clinical practice. In the management of particular paediatric disorders, the potential of microbial manipulation with pre- and probiotics during infancy and childhood is increasingly being investigated. This book presents the evidence supporting their use in practice and reviews safety aspects. Microbiota in health and disease: from pregnancy to childhood has the ambition to provide the reader with an overview of the most recent and stunning advances in the field of infant and child microbiota and their role in health, disease and prevention. As such, it is an excellent resource for health care professionals, students and researchers in the field of life sciences.