The Value of BCG and TNF in Autoimmunity Books

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The Value of BCG and TNF in Autoimmunity


The Value of BCG and TNF in Autoimmunity
  • Author : Denise Faustman
  • Publisher : Academic Press
  • Release : 2014-03-13
  • ISBN : 9780128004616
  • Language : En, Es, Fr & De
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The Value of BCG and TNF in Autoimmunity provides an overview of current research and thinking related to tumor necrosis factor (TNF) induction and the use of the bacillus Calmette-Guérin (BCG) vaccine as potential treatment approaches to diverse forms of autoimmunity. BCG, commonly known as an anti-tuberculosis vaccine, is being explored in worldwide clinical trials as an approach to the treatment of certain forms of autoimmunity. The scope of research behind this therapeutic approach spans from the basic science of TNF signaling to research in diverse autoimmune disciplines, such as type 1 diabetes and multiple sclerosis. Overall, the book focuses on the lessons that can be learned from the researchers' individual experiences and data, and provides a rationale for bringing the inexpensive, generic BCG vaccine to the forefront of clinical trials in different forms of autoimmunity. Editor awarded 2005: Oprah Achievement Award," Top Health Breakthrough by a Female Scientist" Brings into one resource the international scientific literature on a unique way to treat autoimmunity Provides a different perspective on treatment approaches for certain autoimmune conditions Discusses TNF induction, rather than anti-TNF, as a therapeutic pathway for autoimmunity treatment

Idiotypes in Medicine Autoimmunity Infection and Cancer


Idiotypes in Medicine  Autoimmunity  Infection and Cancer
  • Author : R.C. Kennedy
  • Publisher : Elsevier
  • Release : 1997-11-19
  • ISBN : 0080534430
  • Language : En, Es, Fr & De
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This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

Infections in Systemic Autoimmune Diseases Risk Factors and Management Volume 16


Infections in Systemic Autoimmune Diseases  Risk Factors and Management  Volume 16
  • Author : James Galloway
  • Publisher : Handbook of Systemic Autoimmun
  • Release : 2020-03-16
  • ISBN : 9780444642172
  • Language : En, Es, Fr & De
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Infections in Systemic Autoimmune Diseases: Risk Factors and Management, Volume Sixteen describes the state-of-the-art of the risk factors and management treating the most common systemic autoimmune diseases (SADS). This updated volume consists of an introductory chapter that provides a brief overview of what different types of infectious diseases exist, followed by eight chapters detailing risk factors, guidelines and recommendations per different disease and bacterial infections. International in scope, the list of more than 20 contributors from Europa and America reads like a who's who of clinical researchers in the field.

Novel Vaccination Strategies


Novel Vaccination Strategies
  • Author : Stefan H. E. Kaufmann
  • Publisher : John Wiley & Sons
  • Release : 2006-01-24
  • ISBN : 9783527606092
  • Language : En, Es, Fr & De
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The protection mode of most available vaccines is based on antibody responses. Since efficient immune responses to many pathogens rely on activating all arms of the immune system, traditional vaccine development does not provide efficient protection against many diseases. Novel vaccination strategies need to allow presentation of antigens that activate the full array of the immune response in the right composition and should prevent pathogen entry by mobilizing the mucosal immune response. New technological advances optimize the immunogenicity of 'live' and sub-unit vaccines. This book offers an interdisciplinary overview on research and future strategies for rational vaccine design based on recent developments in molecular biology and immunology. It covers new aspects of the immunological interplay between prokaryotic and eukaryotic systems as well as achievements in the development of novel vaccine candidates. Chapters on edible vaccines, on vaccines against bioterror agents and on economical and safety aspects of novel vaccine development round off this title.

Vaccines and Autoimmunity


Vaccines and Autoimmunity
  • Author : Yehuda Shoenfeld
  • Publisher : John Wiley & Sons
  • Release : 2015-07-07
  • ISBN : 9781118663431
  • Language : En, Es, Fr & De
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In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.