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Unraveling the Complexities of Metastasis


Unraveling the Complexities of Metastasis
  • Author : Ammad Ahmad Farooqi
  • Publisher : Academic Press
  • Release : 2020-09-15
  • ISBN : 0128217898
  • Language : En, Es, Fr & De
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Unraveling the Complexities of Metastasis: Transition from a Segmented View to a Conceptual Continuum provides a critical overview of the recent developments of metastasis research and how progress can be further enhanced in the field. Metastasis is a highly complicated mechanism and prognostic analysis of different metastatic patterns in advanced cancer patients is becoming increasingly problematic. It is therefore essential to take a step back and focus on the underlying mechanisms of metastasis before moving ahead for effective translation of laboratory findings to clinically effective therapeutics. This book is surely helpful in putting together missing pieces of an incomplete jig-saw puzzle of molecular cancer. The book discusses topics such as the role of TRAIL-mediated signaling, late metastasis and mechanisms underlying tumor cell dormancy, CTCs and exomes, non-coding way of metastasis, and stem cells. Additionally, it brings relevant and updated information on nanotechnology-based docetaxel and the peculiarities of cancer cell metabolism. This book is a valuable source for cancer researchers, medical doctors and several members of biomedical field who need to understand better the complex mechanism of metastasis. Explains the mechanism of metastasis from basic to advanced level through easy and comprehensive chapters written by internationally distinguished researchers Provides simplified version of important process of metastasis for the readers to comprehend the latest advancements made in the field Presents colorful diagrams to make different aspects of scientifically difficult topics easier for young researchers and new-comers in the field of cancer metastasis

Index Medicus


Index Medicus
  • Author :
  • Publisher :
  • Release : 2004
  • ISBN : OSU:32436011091731
  • Language : En, Es, Fr & De
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ICRDB Cancergram


ICRDB Cancergram
  • Author :
  • Publisher :
  • Release : 1986
  • ISBN : MINN:30000010709891
  • Language : En, Es, Fr & De
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Metastasis Research Protocols


Metastasis Research Protocols
  • Author : Susan A. Brooks
  • Publisher : Springer Science & Business Media
  • Release : 2001
  • ISBN : 9781592591367
  • Language : En, Es, Fr & De
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Although ninety percent of fatal cancer cases involve the spread of a primary tumor, the formation of metastases is still a poorly understood, complex process and a significant problem in the treatment of cancer patients. In Metastasis Research Protocols, leading international investigators describe the key methods needed to investigate why and how metastasis occurs. Volume I of this two-volume set, Analysis of Cells and Tissues, presents a comprehensive collection of established and leading-edge techniques for analyzing the expression of key molecules and for examining their production at the genetic level. The work focuses on the analysis and mapping of molecules produced by cells and tissues, and on the molecular biology underlying their expression. The traditional methods range from the histopathological and the immunocytochemical to SDS-PAGE, Western blotting, and enzyme zymography. Newer and more specialized techniques for analyzing the genetic aspects of metastasis include in situ hybridization to localize mRNAs, FISH, CGH, methylation analysis of CpG islands, RT-PCR, and differential display. The second volume of this set, Analysis of Cell Behavior In Vitro and In Vivo, moves to the level of living cells and tissues to present methodologies applicable to examining metastatic behavior in vitro and in the whole animal. Comprehensive and authoritative, the two volumes of Metastasis Research Protocols constitute a gold-standard collection of readily reproducible methods for understanding the metastatic cascade-first at the cellular and molecular levels, then at the level of the whole organism-responsible for the spread of cancer and for developing novel strategies to combat its spread.

Cancer Ecosystems


Cancer Ecosystems
  • Author : Ubaldo E. Martinez-Outschoorn
  • Publisher : Frontiers Media SA
  • Release : 2019-11-27
  • ISBN : 9782889631759
  • Language : En, Es, Fr & De
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